Foresight Diagnostics Delivers MRD Results in Minutes
About Foresight Diagnostics
Foresight Diagnostics is a precision-oncology company in Colorado. Its CLARITY and PhasED-Seq assays are ultra-sensitive circulating-tumor-DNA (ctDNA) tests that detect minimal residual disease (MRD) early, long before a relapse is visible on a scan.
With major venture funding and a 2025 global kit-development partnership with QIAGEN, Foresight’s lab now supports pharmaceutical trials and cancer centers across five continents.
The Challenge
Data Expanding at an Unprecedented Scale
As Foresight expanded its global reach and product offerings, it faced several operational hurdles in managing the massive data it generated:
- Skyrocketing Data Volume: Each whole-genome ctDNA sequencing file can exceed 250 GB, far too large for email or typical file-sharing tools. Managing and transferring these immense files quickly and securely became a significant challenge.
- Multi-Cloud Complexity: The lab was migrating workloads from Google Cloud to AWS, while some partners still relied on Google buckets or on-prem storage. This created a fragmented environment where maintaining multiple transfer methods and access keys drained IT bandwidth.
- Security and Compliance: As an oncology diagnostics provider handling HIPAA-covered data for certain projects and highly confidential pharmaceutical trial data for others, Foresight needed a solution that could provide airtight security, provable audit trails, SIEM integration, and SSO.
- Unreliable Notifications: Missed or delayed “your results are ready” alerts risked slowing down trial timelines and frustrating clinicians, creating a potential bottleneck in urgent treatment decision-making.
- Growth Pressure: New pharma partnerships required the IT team to rapidly scale external user accounts and set up dozens of new Managed File Transfer connections, putting pressure on the existing infrastructure.
Foresight’s previous approach of granting partners direct access to S3 or GCS buckets didn’t scale. It lacked granular permissions, had thin audit logs, and was unusable for non-technical partners.
The Files.com Solution
Foresight Diagnostics turned to Files.com to address these challenges and consolidate file transfer operations. Key elements of the solution:
- Unified Portal: One branded portal with Okta SSO. Investigators, CROs, and hospital staff get data through granular folder permissions, without seeing S3 keys or bucket paths.
- Cloud-Native Connectors: Direct, agent-based mounts to AWS and GCS. Foresight migrates workloads across hyperscaler platforms at its own pace; partners on either cloud see one unified interface.
- SIEM-Ready Logging: Real-time log streaming to Rapid7 lets the security team monitor file access continuously. Automated alerts surface anomalies as they happen.
- Resilient Notifications: Built-in retry logic and webhook-to-Mailgun workflows keep “results ready” emails on time, even during high-volume transfer periods. Clinicians stay in the loop.
The Results
Immediate improvements unlocked
The transition to Files.com brought immediate and lasting benefits for Foresight Diagnostics:
- Faster Patient Impact: Clinicians receive MRD results within minutes of posting. Days come off decision cycles for relapse-risk patients, and pharma trial timelines accelerate.
- Major Reduction in IT Overhead: Ad-hoc bucket sharing and manual log pulls are gone. The lean IT team has stopped troubleshooting file transfers and can focus on cloud migration and lab capability work.
- Audit-Ready Compliance: Centralized permissions, immutable logs, and SIEM dashboards give the security team immediate evidence for HIPAA and partner audits, with no last-minute scrambles.
- Fast Partner Onboarding: New trial sites and CROs are provisioned in hours, not weeks. Foresight can act on global growth opportunities like the QIAGEN partnership without delay.
- Future-Proof Flexibility: New cloud regions, additional cloud platforms, in-house compute. The Files.com Agent and multi-cloud connectors keep operations running as the lab evolves. Foresight grows without re-architecting workflows.
“Clinicians now receive MRD results within minutes of posting, shaving days off decision cycles for relapse-risk patients.”
Scaling Confidently with Files.com
With Files.com in place, Foresight Diagnostics turned a fragmented, cumbersome data-transfer process into a secure, scalable platform.
Consolidating every transfer workflow into one platform lets Foresight move cancer-test results faster, with stronger security and far less operational drag.
Files.com now anchors Foresight’s global delivery strategy, supporting urgent pharma trials and clinical decisions worldwide.
As Foresight grows in precision oncology, Files.com keeps every data transfer secure, compliant, and on time.